Which types of tablets should never be crushed?

The correct response focuses on enteric-coated and time-released tablets, which should never be crushed due to their specific formulations designed to deliver medication effectively.

Enteric-coated tablets have a protective layer that prevents dissolution in the acidic environment of the stomach. Instead, they are designed to dissolve in the more alkaline environment of the small intestine. Crushing these tablets would alter their release mechanism, potentially leading to stomach irritation or decreased efficacy of the medication.

Time-released tablets, also known as extended-release or sustained-release formulations, are engineered to release the active ingredient slowly over a specified period. Crushing these tablets can release a large dose of the medication all at once, which can increase the risk of side effects and toxicity.

By preserving the integrity of these specialized tablets, patients receive the medication at the intended rate and in the intended location in the gastrointestinal tract, ensuring optimal therapeutic effects.