What is a disadvantage of enteric coated tablets?

The correct answer highlights a significant characteristic of enteric-coated tablets. These tablets are designed to withstand the acidic conditions of the stomach and dissolve in the more neutral or alkaline environment of the intestines. This special coating is crucial for ensuring that the medication is released at the appropriate site in the digestive tract, which can enhance absorption and minimize gastric irritation.

Because of this coating, enteric-coated tablets cannot be crushed or chewed. Doing so would compromise the coating's integrity, potentially leading to premature dissolution in the stomach, which could negate the intended therapeutic effects and increase the risk of side effects. This illustrates the importance of adhering to the specific administration guidelines for these types of medications to ensure they work effectively.

In contrast, options suggesting that enteric-coated tablets must be taken with food or cause more stomach upset do not accurately reflect their intended use. While some medications may require food to enhance absorption, enteric-coated tablets are specifically designed to avoid irritation rather than induce it. Similarly, they are not meant to easily dissolve in water, which distinguishes them from regular formulations that can be easily modified prior to ingestion.